While the utilization of Information System is widely regarded to have a great effect on employee productivity, and acceptance, past research has found inconsistent associations between IS usage and employee productivity. The aim of this study is to know the effect of Information System Usage on Employee Productivity if whether it is the use of IS by the young BRALIRWA’s employees that makes them to do better or the older who are not interested in IS perform better. The IS usage variable investigated included IS usability, IS quality, technology interaction and task-technology adaptation while the dependent variable was employee productivity with work time reduction, innovation and creativity, cost reduction, competitiveness and motivation as the indicators. The study focused on employees in Bralirwa, Rwanda. This study used self-administered questionnaire as the instrument to gather data. The study was done in the two branches; Limonaderie of Kigali and the brewery of Gisenyi. This study used descriptive cross-sectional research design. The population of this study were all the 546 employees comprised of the employees in the branches of Bralirwa LTD. Sample size was calculated using the Krejcie & Morgan (2010) table in selecting the employees; it was derived from the study population of 546 employees working at the Company and came up with target population of 226 employees. Data that was gathered in this study was coded and entered into SPSS which was the software to be used in for data analysis. The study found out that in Bralirwa Company, employee productivity was high as the researcher found a mean of 4.326. Information system was used almost every time, and the study also found that information system usability, quality, technology interaction and technology adaptation effected Bralirwa employee to a large extent as evidence by the means of 3.986, 3.972, 3.996 and 4.022 respectively. The study found that there was a significant relation between employee productivity and IS usage (sig = 0.000). Among IS users, employee productivity has a positive weak and moderate relationship with IS usage, technology interaction and adaptation respectively. With reference to findings of this study, for Bralirwa Company, Rwanda to enhance employee productivity, it should improve on the quality of information system