This study explored factors influencing attitudes towards participation in industrial action of nurses in public hospitals in Nandi County, Kenya. Pertinent factors such as personal values, professional commitment, service commitment, and job satisfaction were explored. A cross-sectional survey was done using the quantitative design where 191 nurses participated in the study. The data analysis was done using descriptive statistics, Pearson product-moment correlation coefficient, t- test for independent samples, and one-way analysis of variance. Results show that nurses have a moderately positive attitude towards participation in industrial action with an overall value of M=2.5743, SD=0.61609, have moderately positive personal values with M=3.2887, SD=.49909, have an average professional commitment with M=3.3303, SD=0.48564, have high service commitment at M=3.6272, SD=0.45130, and are moderately satisfied with their job at M=3.4993 and SD=0.46256. The level of professional and service commitment does not influence the nurses’ attitudes towards participation in industrial action. Nurses who have positive values and high job satisfaction are less likely to participate in industrial action. Both male and female nurses have moderately positive attitudes towards participation in industrial action. The mean attitudes reveal that nurses aged 20 to 30 years have moderately negative attitudes while nurses aged 31 years and above have moderately positive attitudes towards participation in industrial action. Nurses who have served for 5 years and below have moderately negative attitudes while those who have served for 6 years and above have moderately positive attitudes towards participation in industrial action. Therefore, imparting sound personal values among nurses and providing a conducive working environment that fosters job satisfaction for nurses is paramount in combating industrial action.